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Tg(Arc-cre/ERT2)MRhn
Transgene Detail
Nomenclature
Symbol: Tg(Arc-cre/ERT2)MRhn
Name: transgene insertion M, Rene Hen
MGI ID: MGI:5607252
Synonyms: ArcCreERT2
Transgene: Tg(Arc-cre/ERT2)MRhn  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J x CBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsBacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-429N15) containing the entire mouse activity regulated cytoskeletal-associated protein (Arc) gene. A CreERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain), followed by a SV40 polyadenylation sequence, was inserted into the translation initiation site of the gene. Founder lines M and F were established and maintained. (J:215456)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Arc     Summary of all recombinase alleles driven by Arc. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:215456 Denny CA, et al., Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron. 2014 Jul 2;83(1):189-201
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory