Gimap8^tm1.1Gwb
Targeted Allele Detail

Summary

• Symbol: Gimap8^tm1.1Gwb
• Name: GTPase, IMAP family member 8; targeted mutation 1.1, Geoffrey W Butcher
• MGI ID: MGI:5607134
• Synonyms: Gimap8^-
• Gene: Gimap8 Location: Chr6:48624168-48637809 bp, + strand Genetic Position: Chr6, 23.62 cM
• Alliance: Gimap8^tm1.1Gwb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215741
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This mutation was generated by cre recombinase excision of loxP flanked exons 3 and 4 leaving a single loxP site. RNA splicing of exon 2 to exon 5 is predicted to result in a reading-frame shift. (J:215741)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gimap8 Mutation: 34 strains or lines available

References

• Original: J:215741 Webb LM, et al., Generation and characterisation of mice deficient in the multi-GTPase domain containing protein, GIMAP8. PLoS One. 2014;9(10):e110294
• All: 1 reference(s)