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Targeted Allele Detail
Symbol: Srftm1.1Wtp
Name: serum response factor; targeted mutation 1.1, William T Pu
MGI ID: MGI:5606035
Synonyms: CVDC/B2B program mutation, Srf-flbio
Gene: Srf  Location: Chr17:46859255-46867101 bp, - strand  Genetic Position: Chr17, 22.9 cM
Germline Transmission:  Earliest citation of germline transmission: J:185868
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Project Collection: B2B/CvDC
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to insert a FLAG/bio epitope tag and a frt-flanked neomycin resistance (neo) cassette at the endogenous Srf stop codon and upstream of the 3' UTR. FLP mediated recombination removed the FRT-flanked neo cassette. (J:185868)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Srf Mutation:  16 strains or lines available
Original:  J:185868 Schramm C, Information about alleles developed by members of the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory