Cd109^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cd109^{tm1.1(KOMP)Vlcg}
• Name: CD109 antigen; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5605817
• Gene: Cd109 Location: Chr9:78522828-78623535 bp, + strand Genetic Position: Chr9, 43.65 cM
• Alliance: Cd109^{tm1.1(KOMP)Vlcg} page
• IMPC: Cd109 gene page

Mutation origin

• Mutant Cell Line: 12144H-A4
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: Cre-mediated recombination of the parental Cd109^{tm1(KOMP)Vlcg} allele resulted in the removal of the neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cd109 Mutation: 102 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 3 reference(s)