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Brinp1tm1.1Pib
Targeted Allele Detail
Nomenclature
Symbol: Brinp1tm1.1Pib
Name: bone morphogenic protein/retinoic acid inducible neural specific 1; targeted mutation 1.1, Phillip I Bird
MGI ID: MGI:5604542
Gene: Brinp1  Location: Chr4:68761514-68954397 bp, - strand  Genetic Position: Chr4, 35.03 cM, cytoband C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:231288
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis mutation was generated from the conditional allele by cre recombinase excision of exon 3 and a frt sequence-flanked neomycin resistance cassette in intron 3, leaving a single loxP site. (J:231288)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brinp1 Mutation:  17 strains or lines available
References
Original:  J:231288 Berkowicz SR, et al., Brinp1 (-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density. Mol Autism. 2016;7:22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory