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Tg(Th-EGFP)6-7Okn
Transgene Detail
Nomenclature
Symbol: Tg(Th-EGFP)6-7Okn
Name: transgene insertion 6-7, Hideyuki Okano
MGI ID: MGI:5604271
Synonyms: TH-GFP
Transgene: Tg(Th-EGFP)6-7Okn  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains 9.0 kb of upstream sequence from the rat tyrosine hydroxylase gene, the second intron of the rabbit beta-globin gene, the EGFP coding sequence and the rabbit beta-globin and SV40 polyadenylation signals. GFP expression is observed in dopaminergic neurons in the embryonic ventral mesencephalons and in the substantia nigra of the adult midbrain. (J:186830)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:186830 Sawamoto K, et al., Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6423-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory