Gt(ROSA)26Sor^{tm1(Tbx1)Rche}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Tbx1)Rche}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ellen R Richie
• MGI ID: MGI:5604017
• Synonyms: R26^iTbx, R26^iTbx1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Tbx1)Rche} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214094
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus a full-length mouse Tbx1 cDNA and an IRES-EGFP downstream of a floxed beta-geo stop cassette. Cre excision of the stop cassette results in expression of Tbx1 and EGFP. (J:214094)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:214094 Reeh KA, et al., Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development. 2014 Aug;141(15):2950-8
• All: 1 reference(s)