Tshz1^tm2Garr
Targeted Allele Detail

Summary

• Symbol: Tshz1^tm2Garr
• Name: teashirt zinc finger family member 1; targeted mutation 2, Alistair N Garratt
• MGI ID: MGI:5588815
• Synonyms: Tshz1^{flox frt Neo}
• Gene: Tshz1 Location: Chr18:84029752-84105831 bp, - strand Genetic Position: Chr18, 57.53 cM
• Alliance: Tshz1^tm2Garr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209428
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and frt-flanked kanamycin/neomycin resistance cassette was inserted into intron upstream of exon2, and another loxP site was inserted into intron downstream of exon2 of Tshz1 gene by homologous recombination. (J:209428)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tshz1 Mutation: 52 strains or lines available

References

• Original: J:209428 Ragancokova D, et al., TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27
• All: 1 reference(s)