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Dennd2dtm2b(KOMP)Mbp
Targeted Allele Detail
Nomenclature
Symbol: Dennd2dtm2b(KOMP)Mbp
Name: DENN/MADD domain containing 2D; targeted mutation 2b, Mouse Biology Program, University of Californib, Davis
MGI ID: MGI:5587052
Gene: Dennd2d  Location: Chr3:106482431-106503030 bp, + strand  Genetic Position: Chr3, 46.49 cM
Mutation
origin
Mutant Cell Line:  DEPD00581_2_D04
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre-mediated excision of the parental Dennd2dtm2a(KOMP)Mbp allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dennd2d Mutation:  0 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory