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Transgene Detail
Symbol: Tg(FXN)Y47Pook
Name: transgene insertion Y47, Mark A Pook
MGI ID: MGI:5585461
Synonyms: Y47
Transgene: Tg(FXN)Y47Pook  Location: unknown  
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Tg(FXN)Y47Pook expresses 1 gene
Mutation detailsThe transgene construct consists of a 370 kbp YAC (Y37FA12) that includes the entire human FXN gene with nine GAA repeats [(GAA)>9<] at the mutation locus within intron 1 of FXN. The GAA repeat expansion was not further modified. Founder line Y47 was established and contains a single copy integration of the transgene. (J:213628)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Original:  J:213628 Pook MA, et al., Rescue of the Friedreich's ataxia knockout mouse by human YAC transgenesis. Neurogenetics. 2001 Oct;3(4):185-93
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory