Del(5Gtf2i-Gtf2ird1)2Lro
Targeted Allele Detail

Summary

• Symbol: Del(5Gtf2i-Gtf2ird1)2Lro
• Name: deletion, Chr 5, L Osborne 2
• MGI ID: MGI:5584299
• Synonyms: Del2Lro
• Gene: Del(5Gtf2i-Gtf2ird1)2Lro Location: unknown Genetic Position: Chr5, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212307
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(5Gtf2i-Gtf2ird1)2Lro involves 2 genes/genome features (Gtf2i, Gtf2ird1) View all
• Mutation details: Cre-mediated recombination between loxP sites in intron 4 of Gtf2ird1^{Gt(XS0608)Wtsi} and downstream of exon 34 in Gtf2i^tm1Lro produced a deletion of the intervening sequence. (J:212307, J:222543)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(5Gtf2i-Gtf2ird1)2Lro Mutation: 0 strains or lines available

Notes

ES cell line = E14.1TGa.4 or R1:
Gtf2ird1^{Gt(XS0608)Wtsi} was generated in the E14.1TGa.4 ES cell line, derived from 129P2/OlaHsd, and Gtf2i^tm1Lro was made in the R1 ES cell line, derived from (129X1/SvJ x 129S1/Sv)F1-Kitl⁺.

References

• Original: J:212307 IMGC, Abstracts for the IMGC2014 meeting (October, 2014). 2014
• All: 4 reference(s)