About   Help   FAQ
Ltftm1(icre)Tdku
Targeted Allele Detail
Nomenclature
Symbol: Ltftm1(icre)Tdku
Name: lactotransferrin; targeted mutation 1, Takiko Daikoku
MGI ID: MGI:5581966
Synonyms: Ltf-iCre, Ltftm1(icre,EGFP)Tdku
Gene: Ltf  Location: Chr9:110848360-110871834 bp, + strand  Genetic Position: Chr9, 60.79 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211105
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to replace part of exon1 and intron 1 of the gene with a codon optimized Cre recombinase gene (iCre) followed by an internal ribosome entry site (IRES), an enhanced green fluorescent protein (EGFP), a polyadenylation site, and a frt-flanked neomycin/kanamycin resistance (neo/kan) cassette. (J:211105)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ltf     Summary of all recombinase alleles driven by Ltf. Comparative matrix view of recombinase activities
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ltf Mutation:  27 strains or lines available
References
Original:  J:211105 Daikoku T, et al., Lactoferrin-iCre: A New Mouse Line to Study Uterine Epithelial Gene Function. Endocrinology. 2014 Jul;155(7):2718-24
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory