Gt(ROSA)26Sortm1(Gck)Ydor
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(Gck)Ydor |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Yuval Dor |
MGI ID: |
MGI:5581726 |
Synonyms: |
mutGCK |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(Gck)Ydor page
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Germline Transmission: |
Earliest citation of germline transmission:
J:210493
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, Constitutively active, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(Gck)Ydor expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
rat |
Gck (24385) |
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Mutation details: The trgeting construct introduced into the locus a floxed STOP cassette, a rat cDNA with an activating amino acid substitution of cysteine for tyrosine at position 214 (Y214C), an IRES sequence and an EGFP reporter.
(J:210493)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:210493 Tornovsky-Babeay S, et al., Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in beta cells. Cell Metab. 2014 Jan 7;19(1):109-21 |
All: |
1 reference(s) |
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