Myf5tm2Pas
Targeted Allele Detail
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Symbol: |
Myf5tm2Pas |
Name: |
myogenic factor 5; targeted mutation 2, Institut Pasteur |
MGI ID: |
MGI:5581636 |
Synonyms: |
myf-5a1, Myf5nlacZ, Myf5-nlacZ, Myf5/nlacZ |
Gene: |
Myf5 Location: Chr10:107318769-107321995 bp, - strand Genetic Position: Chr10, 55.95 cM
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Alliance: |
Myf5tm2Pas page
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Germline Transmission: |
Earliest citation of germline transmission:
J:16491
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Parent Cell Line: |
D3 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An nLacZ gene is fused in-frame to the DNA sequences encoding the first 13 amino acids introducing a small deletion and resulting in a disruption of the gene and expression of nLacZ under the transcriptional regulation of the endogenous promoter. A TK-neomycin resistance cassette was inserted downstream of the reporter gene. In-situ hybridization analysis indicates that Myf5 and Myf6 expression is absent.
(J:16491, J:33706)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Myf5 Mutation: |
17 strains or lines available
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Original: |
J:16491 Tajbakhsh S, et al., Mouse limb muscle is determined in the absence of the earliest myogenic factor myf-5. Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):747-51 |
All: |
32 reference(s) |
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