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Rcor1tm2.1Gman
Targeted Allele Detail
Nomenclature
Symbol: Rcor1tm2.1Gman
Name: REST corepressor 1; targeted mutation 2.1, Gail Mandel
MGI ID: MGI:5581612
Synonyms: Rcor1flox
Gene: Rcor1  Location: Chr12:111039367-111115902 bp, + strand  Genetic Position: Chr12, 60.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211681
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was introduced to intron 3 and a FRT-PGK-Neo-pA-splice donor-FRT-loxP cassette was placed in intron 4. Flpe mediated recombination removed the FRT-flanked neo cassette leaving loxP sites on either side of exon 4. (J:211681)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rcor1 Mutation:  33 strains or lines available
References
Original:  J:211681 Yao H, et al., Corepressor Rcor1 is essential for murine erythropoiesis. Blood. 2014 May 15;123(20):3175-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory