About   Help   FAQ
Crhm1H
Chemically induced Allele Detail
Nomenclature
Symbol: Crhm1H
Name: corticotropin releasing hormone; mutation 1, Harwell
MGI ID: MGI:5578654
Synonyms: Crh-120
Gene: Crh  Location: Chr3:19693401-19695396 bp, - strand  Genetic Position: Chr3, 5.75 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Applicable)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to C point mutation at -120 bp with reference to a transcription start (NM_205769) at the consensus sequence of a caudal-type homeobox response element (CDXARE). (J:208708)
Inheritance:    Dominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crh Mutation:  26 strains or lines available
References
Original:  J:208708 Bentley L, et al., An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess. Endocrinology. 2014 Mar;155(3):908-22
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/09/2018
MGI 6.11
The Jackson Laboratory