Ampd3^MRI49372
Chemically induced Allele Detail

Summary

• Symbol: Ampd3^MRI49372
• Name: adenosine monophosphate deaminase 3; MRI49372
• MGI ID: MGI:5578570
• Synonyms: Ampd3^T689A
• Gene: Ampd3 Location: Chr7:110367413-110411612 bp, + strand Genetic Position: Chr7, 57.85 cM, cytoband E2-E3
• Alliance: Ampd3^MRI49372 page

Mutation origin

• Strain of Origin: SJL/J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Undefined
• Mutation details: The molecular lesion is an A-to-G base substitution at location 7:117953361. This results in a substitution of alanine for threonine at position 689 in the encoded protein. (J:236531)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ampd3 Mutation: 37 strains or lines available

References

• Original: J:236531 Hortle E, et al., Adenosine monophosphate deaminase 3 activation shortens erythrocyte half-life and provides malaria resistance in mice. Blood. 2016 Sep 1;128(9):1290-301
• All: 1 reference(s)