Tg(Isl1-lacZ)5Cka
Transgene Detail

Summary

• Symbol: Tg(Isl1-lacZ)5Cka
• Name: transgene insertion 5, Claudia Kappen
• MGI ID: MGI:5578567
• Synonyms: 3cF10
• Transgene: Tg(Isl1-lacZ)5Cka Location: unknown
• Alliance: Tg(Isl1-lacZ)5Cka page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct contains the lacZ reporter under the control of a 10 kb Isl1 fragment. The Isl1 insert consists of a region beginning 8.5 kb downstream of the transcription start site and ending 7 kb downstream of the transcription stop site, and including an enhancer regulatory element. LacZ reporter activity parallels endogenous gene expression in the developing heart as well as visceral and posterior mesoderm. (J:212308)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:212308 Kappen C, et al., Identification of regulatory elements in the Isl1 gene locus. Int J Dev Biol. 2009;53(7):935-46
• All: 1 reference(s)