About   Help   FAQ
Lamb2npht
Chemically induced Allele Detail
Nomenclature
Symbol: Lamb2npht
Name: laminin, beta 2; nephertiti
MGI ID: MGI:5578541
Gene: Lamb2  Location: Chr9:108479736-108490530 bp, + strand  Genetic Position: Chr9, 59.4 cM, cytoband F1
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a G to A point mutation that results in the amino acid substitution of tyrosine for cysteine at position 185 (C185Y).
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lamb2 Mutation:  38 strains or lines available
References
Original:  J:208069 Bull KR, et al., Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome. J Pathol. 2014 May;233(1):18-26
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/09/2018
MGI 6.11
The Jackson Laboratory