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KitW-85J
Spontaneous Allele Detail
Nomenclature
Symbol: KitW-85J
Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting 85 Jackson
MGI ID: MGI:5578539
Gene: Kit  Location: Chr5:75735647-75817382 bp, + strand  Genetic Position: Chr5, 39.55 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Spontaneous (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsA spontaneous C-to-T transition in Chromosome 5 position 75,652,822 (GRCm38) results in an arginine to tryptophan mutation at position 890 (p.R890W). (J:212309)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kit Mutation:  149 strains or lines available
References
Original:  J:212309 Harris BS, et al., Dominant spotting 85 Jackson. MGI Direct Data Submission. 2014;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory