Tg(ACTA1-SLC8A1)4Jmol
Transgene Detail

Summary

• Symbol: Tg(ACTA1-SLC8A1)4Jmol
• Name: transgene insertion 4, Jeffery Molkentin
• MGI ID: MGI:5578228
• Synonyms: NCX1 TG
• Transgene: Tg(ACTA1-SLC8A1)4Jmol Location: unknown
• Alliance: Tg(ACTA1-SLC8A1)4Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA1-SLC8A1)4Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  dog	SLC8A1 (475738)

• Mutation details: Canine SLC8A1 (also called NCX1) cDNA is expressed under the regulatory control of the human skeletal muscle-specific alpha actin promoter with a slow troponin (Tnnc1) enhancer. (J:212146)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:212146 Burr AR, et al., Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Mol Cell Biol. 2014 Jun;34(11):1991-2002
• All: 1 reference(s)