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Transgene Detail
Symbol: Tg(ACTA1-SLC8A1)4Jmol
Name: transgene insertion 4, Jeffery Molkentin
MGI ID: MGI:5578228
Synonyms: NCX1 TG
Transgene: Tg(ACTA1-SLC8A1)4Jmol  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(ACTA1-SLC8A1)4Jmol expresses 1 gene
Mutation detailsCanine SLC8A1 (also called NCX1) cDNA is expressed under the regulatory control of the human skeletal muscle-specific alpha actin promoter with a slow troponin (Tnnc1) enhancer. (J:212146)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:212146 Burr AR, et al., Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice. Mol Cell Biol. 2014 Jun;34(11):1991-2002
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory