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Tg(Alb-PDGFC)#Jcam
Transgene Detail
Nomenclature
Symbol: Tg(Alb-PDGFC)#Jcam
Name: transgene insertion, Jean S Campbell
MGI ID: MGI:5578131
Synonyms: PDGF-C Tg
Transgene: Tg(Alb-PDGFC)#Jcam  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Alb-PDGFC)#Jcam expresses 1 gene
 
Mutation detailsThis transgene consists of a 1,058-bp fragment containing the human PDGFC open reading frame between the mouse albumin enhancer/proximal promoter with an adjacent 5' rat insulin II intron and a human growth hormone polyadenylation sequence. Human PDGFC expression in the liver was detected only in one line, however, the pound symbol (#) is used because the line number is not specified. (J:96979)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:96979 Campbell JS, et al., Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3389-94
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory