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Zeb2tm2.1Yhi
Targeted Allele Detail
Nomenclature
Symbol: Zeb2tm2.1Yhi
Name: zinc finger E-box binding homeobox 2; targeted mutation 2.1, Yujiro Higashi
MGI ID: MGI:5574184
Synonyms: Sip1SIP1-EGFP
Gene: Zeb2  Location: Chr2:44983632-45117395 bp, - strand  Genetic Position: Chr2, 27.31 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:207850
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin resistance cassette was inserted upstream of exon 9. A EGFP reporter was inserted in-frame with the coding sequence in exon 9. Cre-mediated recombination removed the selection cassette. (J:207850)
Generation of Zeb2tm2.1Yhi allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zeb2 Mutation:  11 strains or lines available
References
Original:  J:207850 Nishizaki Y, et al., SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014 Jan;52(1):56-67
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory