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Aspmtm1.1Kxi
Targeted Allele Detail
Summary
Symbol: Aspmtm1.1Kxi
Name: abnormal spindle microtubule assembly; targeted mutation 1.1, Kyoko Itoh
MGI ID: MGI:5573151
Synonyms: Aspm flox
Gene: Aspm  Location: Chr1:139382510-139421829 bp, + strand  Genetic Position: Chr1, 61.45 cM, cytoband F
Alliance: Aspmtm1.1Kxi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205524
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:205524)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aspm Mutation:  138 strains or lines available
References
Original:  J:205524 Fujimori A, et al., Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory