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Tg(Igh-ROR1)1Kip
Transgene Detail
Nomenclature
Symbol: Tg(Igh-ROR1)1Kip
Name: transgene insertion 1, Thomas J Kipps
MGI ID: MGI:5571366
Synonyms: ROR1 Tg
Transgene: Tg(Igh-ROR1)1Kip  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Igh-ROR1)1Kip expresses 1 gene
 
Mutation detailsThe human ROR1 is under the control of the B cell specific murine Igh promoter/enhancer (containing the mouse V(H) promoter and Igh-mu-enhancer). One line was made. (J:206368)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:206368 Widhopf GF 2nd, et al., ROR1 can interact with TCL1 and enhance leukemogenesis in Emu-TCL1 transgenic mice. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):793-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory