Tspo^tm1.1Wbd
Targeted Allele Detail

Summary

• Symbol: Tspo^tm1.1Wbd
• Name: translocator protein; targeted mutation 1.1, Wenbin Deng
• MGI ID: MGI:5569290
• Synonyms: Tspofl, TSPO^flox, Tspo^flx
• Gene: Tspo Location: Chr15:83447793-83458404 bp, + strand Genetic Position: Chr15, 39.4 cM
• Alliance: Tspo^tm1.1Wbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207708
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. A loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:207708)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspo Mutation: 14 strains or lines available

References

• Original: J:207708 Morohaku K, et al., Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology. 2014 Jan;155(1):89-97
• All: 8 reference(s)