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Tg(LTF-EGFP/cre/PGR)15Klin
Transgene Detail
Nomenclature
Symbol: Tg(LTF-EGFP/cre/PGR)15Klin
Name: transgene insertion 15, Kurt Lin
MGI ID: MGI:5568730
Synonyms: Lf-GCrePR1e, Tg(LTF-EGFP/Cre/PR1e)15Klin
Transgene: Tg(LTF-EGFP/cre/PGR)15Klin  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/NJNarl
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    mifepristone
Mutation:    Insertion
 
Mutation detailsA construct was generated with a triple-fusion sequence EGFP/cre/PGR (encoding EGFP, cre recombinase, and the human progesterone ligand binding domain - aa F642-L901 of LBD). The fusion gene was cloned downstream of the human lactoferrin promoter (LTF). The LfB-GCrePR1e construct was used for microinjection and 12 founders were obtained. Four founders (#'s 7, 11, 15, and 27) were crossed to R26-lacZ reporter mice. Line 15 was used to generate most of the results in the original study. (J:209793)
Structure of Tg(LTF-EGFP/cre/PGR)15Klin.
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: LTF     Summary of all recombinase alleles driven by LTF.
 

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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:209793 Chen MR, et al., RU486-inducible recombination in the salivary glands of lactoferrin promoter-driven green fluorescent Cre transgenic mice. Genesis. 2010 Oct 1;48(10):585-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory