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Lats1tm1.1Jfm
Targeted Allele Detail
Nomenclature
Symbol: Lats1tm1.1Jfm
Name: large tumor suppressor; targeted mutation 1.1, James F Martin
MGI ID: MGI:5568586
Synonyms: Lats1f
Gene: Lats1  Location: Chr10:7556978-7592224 bp, + strand  Genetic Position: Chr10, 2.29 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206316
Parent Cell Line:  RJ2.2 (ES Cell)
Strain of Origin:  (C57BL/6Brd-Tyrc-Brd x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to flank exon 4 with loxP sites. This construct also contained a frt-flanked neomycin resistance (neo) cassette. FLP-mediated recombination removed the frt-flanked neo cassette. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lats1 Mutation:  29 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory