Ins2^tm1.1Msol
Targeted Allele Detail

Summary

• Symbol: Ins2^tm1.1Msol
• Name: insulin II; targeted mutation 1.1, Michele Solimena
• MGI ID: MGI:5568498
• Synonyms: mIns2-SNAP
• Gene: Ins2 Location: Chr7:142232393-142233463 bp, - strand Genetic Position: Chr7, 88.0 cM
• Alliance: Ins2^tm1.1Msol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208929
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A SNAP reporter was inserted into exon 3 upstream of the STOP codon to generate a fusion reporter product. Flp-mediated recombination removed the FRT-flanked neomcyin resistance cassette inserted downstream of the STOP codon. (J:208929)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ins2 Mutation: 90 strains or lines available

References

• Original: J:208929 Ivanova A, et al., Age-dependent labeling and imaging of insulin secretory granules. Diabetes. 2013 Nov;62(11):3687-96
• All: 1 reference(s)