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Akt1tm1Zzy
Targeted Allele Detail
Nomenclature
Symbol: Akt1tm1Zzy
Name: thymoma viral proto-oncogene 1; targeted mutation 1, Zhongzhou Yang
MGI ID: MGI:5563541
Synonyms: Akt1F, Akt1fl
Gene: Akt1  Location: Chr12:112653821-112674796 bp, - strand  Genetic Position: Chr12, 61.2 cM, cytoband F1-F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206783
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    A floxed allele was generated.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akt1 Mutation:  24 strains or lines available
References
Original:  J:206783 Di R, et al., S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt. Biochem J. 2012 Jan 1;441(1):199-207
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory