Fcer2a^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Fcer2a^m1Anu
• Name: Fc receptor, IgE, low affinity II, alpha polypeptide; mutation 1, Australian National University
• MGI ID: MGI:5563468
• Synonyms: ENU18Ch:065a
• Gene: Fcer2a Location: Chr8:3731737-3744175 bp, - strand Genetic Position: Chr8, 1.92 cM, cytoband A1
• Alliance: Fcer2a^m1Anu page

Mutation origin

• Strain of Origin: C57BL/6JAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to A point mutation at position 226 on cDNA (ENSMUST00000005678) in exon 3 and results in the amino acid substitution of Cysteine to STOP at position 18. Reduced protein expression was confirmed in peripheral blood B cells. (J:104190)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Fcer2a Mutation: 24 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 2 reference(s)