About   Help   FAQ
Cd72c
Allele Detail
Nomenclature
Symbol: Cd72c
Name: CD72 antigen; c haplotype
MGI ID: MGI:5563235
Gene: Cd72  Location: Chr4:43447724-43455102 bp, - strand  Genetic Position: Chr4, 23.04 cM
Mutation
origin
Strain of Origin:  various
Mutation
description
Allele Type:    Not Applicable
Mutation:    Not Applicable
 
Mutation detailsThis serological allele is recognized by epitopes 3. Sequence differences between the haplotypes (a, b and c) largely result in amino acid variation in the extracellular domains. The c haplotype contains a 7 amino acid deletion in the C-type lectin-like domain. However, the amino acid sequence of the transmembrane domain and cytoplasmic region is identical to the other hapotype alleles (a, b and d). This allele was identified in the strains AKR, MRL and SJL. (J:1507, J:23623)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd72 Mutation:  15 strains or lines available
Notes
The Cd72c haplotype is a modifier of Faslpr-induced autoimmune disease. J:204782
References
Original:  J:1507 Robinson WH, et al., Extensive polymorphism in the extracellular domain of the mouse B cell differentiation antigen Lyb-2/CD72. J Immunol. 1992 Aug 1;149(3):880-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory