About   Help   FAQ
Targeted Allele Detail
Symbol: Oprm1tm1.2Cgrf
Name: opioid receptor, mu 1; targeted mutation 1.2, Claire Gaveriaux-Ruff
MGI ID: MGI:5561220
Gene: Oprm1  Location: Chr10:6758593-7038209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Germline Transmission:  Earliest citation of germline transmission: J:207536
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 2. A floxed hygromycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette, exon 2 and exon 3. (J:207536)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  36 strains or lines available
Original:  J:207536 Weibel R, et al., Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice. PLoS One. 2013;8(9):e74706
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory