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Tspotm1.1Maf
Targeted Allele Detail
Nomenclature
Symbol: Tspotm1.1Maf
Name: translocator protein; targeted mutation 1.1, Michael A Forte
MGI ID: MGI:5560329
Synonyms: TspoloxP
Gene: Tspo  Location: Chr15:83563592-83574203 bp, + strand  Genetic Position: Chr15, 39.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA FRT site flanked targeting vector containing PGK-Neo selection cassette was utilized in the construction of this mutant. This selection cassette and a loxP site was inserted upstream of exon 2. A second loxP site was inserted downstream of exon 3. Mutant mice were bred with Gt(ROSA)26Sortm1(FLP1)Dym mice (on a C57BL/6 congenic background (N10)) to remove the neo selection cassette. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 21 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tspo Mutation:  12 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory