Stk25^tm1.1Bwh
Targeted Allele Detail

Summary

• Symbol: Stk25^tm1.1Bwh
• Name: serine/threonine kinase 25 (yeast); targeted mutation 1.1, Brian Howell
• MGI ID: MGI:5559695
• Synonyms: Stk25^fl
• Gene: Stk25 Location: Chr1:93548473-93581937 bp, - strand Genetic Position: Chr1, 47.25 cM
• Alliance: Stk25^tm1.1Bwh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203414
• Parent Cell Line: D2 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Homologous recombination inserted a loxP site before exons 4 and 5, a FRT-flanked neo cassette, and followed by another loxP sequence. FLP-mediated recombination removed the neo cassette. (J:203414)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Stk25 Mutation: 23 strains or lines available

References

• Original: J:203414 Matsuki T, et al., Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration. Neural Dev. 2013 Nov 13;8(1):21
• All: 2 reference(s)