Gip^tm1.1Gmost
Targeted Allele Detail

Summary

• Symbol: Gip^tm1.1Gmost
• Name: gastric inhibitory polypeptide; targeted mutation 1.1, Gustavo Mostoslavsky
• MGI ID: MGI:5559592
• Synonyms: GIP-GFP
• Gene: Gip Location: Chr11:95915371-95921657 bp, + strand Genetic Position: Chr11, 59.21 cM
• Alliance: Gip^tm1.1Gmost page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214658
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector containing a loxP site flanked puromycin resistance selection cassette and EGFP (enhanced Green Fluorescent Protein) was used to disrupt exon 2 (including the initiation codon) and part of exon 3. The puromycin cassette was deleted by transiently transfection of an expression vector of Cre recombinase in the ES cells. EGFP expression is observed in the duodenum and jejunum and to a lesser extent in the ileum. (J:101977, J:214658)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gip Mutation: 13 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)