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Giptm1.1Gmost
Targeted Allele Detail
Nomenclature
Symbol: Giptm1.1Gmost
Name: gastric inhibitory polypeptide; targeted mutation 1.1, Gustavo Mostoslavsky
MGI ID: MGI:5559592
Synonyms: GIP-GFP
Gene: Gip  Location: Chr11:95915371-95921657 bp, + strand  Genetic Position: Chr11, 59.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214658
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing a loxP site flanked puromycin resistance selection cassette and EGFP (enhanced Green Fluorescent Protein) was used to disrupt exon 2 (including the initiation codon) and part of exon 3. The puromycin cassette was deleted by transiently transfection of an expression vector of Cre recombinase in the ES cells. EGFP expression is observed in the duodenum and jejunum and to a lesser extent in the ileum. (J:101977, J:214658)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gip Mutation:  14 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory