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Wdpcptm1.1Clo
Targeted Allele Detail
Nomenclature
Symbol: Wdpcptm1.1Clo
Name: WD repeat containing planar cell polarity effector; targeted mutation 1.1, Cecilia W Lo
MGI ID: MGI:5558100
Gene: Wdpcp  Location: Chr11:21571969-21898687 bp, + strand  Genetic Position: Chr11, 13.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205269
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 5 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 5 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 5. (J:205269)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wdpcp Mutation:  15 strains or lines available
References
Original:  J:205269 Cui C, et al., Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013 Nov;11(11):e1001720
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory