Kiss1rtm1.1Aeh
Targeted Allele Detail
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Symbol: |
Kiss1rtm1.1Aeh |
Name: |
KISS1 receptor; targeted mutation 1.1, Allan E Herbison |
MGI ID: |
MGI:5558092 |
Synonyms: |
Gpr54f, Gpr54loxP |
Gene: |
Kiss1r Location: Chr10:79752805-79758107 bp, + strand Genetic Position: Chr10, 39.72 cM
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Alliance: |
Kiss1rtm1.1Aeh page
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Reduced gonadal size in Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh Tg(Gnrh1-cre)1Dlc mice is rescued by the Tg(Gnrh1-Kiss1r)#Aeh transgene
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:206044
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed.
(J:206044)
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Generation of the Kiss1rtm1.1Aeh allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Kiss1r Mutation: |
20 strains or lines available
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Original: |
J:206044 Kirilov M, et al., Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron. Nat Commun. 2013;4:2492 |
All: |
5 reference(s) |
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