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Tbxas1tm1Okun
Targeted Allele Detail
Summary
Symbol: Tbxas1tm1Okun
Name: thromboxane A synthase 1, platelet; targeted mutation 1, Toshiaki Okuno
MGI ID: MGI:5553179
Synonyms: TxAS-
Gene: Tbxas1  Location: Chr6:38852338-39061519 bp, + strand  Genetic Position: Chr6, 17.85 cM, cytoband F1-pter
Alliance: Tbxas1tm1Okun page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:203820
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 12 and 13. RT-PCR confirmed the absence of transcript expression in whole blood cells. (J:203820)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbxas1 Mutation:  30 strains or lines available
References
Original:  J:203820 Matsunobu T, et al., Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. J Lipid Res. 2013 Nov;54(11):2979-87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory