About   Help   FAQ
Tbxas1tm1Okun
Targeted Allele Detail
Nomenclature
Symbol: Tbxas1tm1Okun
Name: thromboxane A synthase 1, platelet; targeted mutation 1, Toshiaki Okuno
MGI ID: MGI:5553179
Synonyms: TxAS-
Gene: Tbxas1  Location: Chr6:38875404-39084585 bp, + strand  Genetic Position: Chr6, 17.85 cM, cytoband F1-pter
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:203820
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 12 and 13. RT-PCR confirmed the absence of transcript expression in whole blood cells. (J:203820)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbxas1 Mutation:  16 strains or lines available
References
Original:  J:203820 Matsunobu T, et al., Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. J Lipid Res. 2013 Nov;54(11):2979-87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/31/2018
MGI 6.12
The Jackson Laboratory