Usp9x^tm1.1Lex
Targeted Allele Detail

Summary

• Symbol: Usp9x^tm1.1Lex
• Name: ubiquitin specific peptidase 9, X chromosome; targeted mutation 1.1, Lexicon Genetics
• MGI ID: MGI:5551903
• Synonyms: Usp9x^loxp
• Gene: Usp9x Location: ChrX:12937737-13039567 bp, + strand Genetic Position: ChrX, 7.95 cM
• Alliance: Usp9x^tm1.1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201577
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6
• Project Collection: Lexicon

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 31. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 31. Flp-mediated recombination removed the resistance cassette and left exon 31 floxed. (J:201577)

Generation of the Usp9x^tm1.1Lex allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp9x Mutation: 24 strains or lines available

References

• Original: J:201577 Huntwork-Rodriguez S, et al., JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis. J Cell Biol. 2013 Sep 2;202(5):747-63
• All: 3 reference(s)