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Kalrntm2Npl
Targeted Allele Detail
Nomenclature
Symbol: Kalrntm2Npl
Name: kalirin, RhoGEF kinase; targeted mutation 2, Neuropeptide Laboratory
MGI ID: MGI:5551304
Synonyms: KalSRCKO
Gene: Kalrn  Location: Chr16:33969073-34573291 bp, - strand  Genetic Position: Chr16, 24.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206512
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 13, an exon in the spectrin repeat region (KalSR), was floxed. Flp-mediated recombination removed the neomycin resistance cassette. (J:206512)
Generation of the Kalrntm2Npl allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kalrn Mutation:  125 strains or lines available
References
Original:  J:206512 Mandela P, et al., Kalrn plays key roles within and outside of the nervous system. BMC Neurosci. 2012;13:136
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory