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Wlstm1.1Arte
Targeted Allele Detail
Nomenclature
Symbol: Wlstm1.1Arte
Name: wntless WNT ligand secretion mediator; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5547720
Synonyms: Evifl, Evifloxed
Gene: Wls  Location: Chr3:159839695-159938670 bp, + strand  Genetic Position: Chr3, 82.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202499
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA puromycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the puromycin resistance cassette and left exon 3 floxed. (J:202499)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wls Mutation:  8 strains or lines available
References
Original:  J:202499 Augustin I, et al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. J Exp Med. 2013 Aug 26;210(9):1761-77
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory