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Tnfrsf21tm1Arte
Targeted Allele Detail
Nomenclature
Symbol: Tnfrsf21tm1Arte
Name: tumor necrosis factor receptor superfamily, member 21; targeted mutation 1, TaconicArtemis
MGI ID: MGI:5546637
Gene: Tnfrsf21  Location: Chr17:43016555-43089188 bp, + strand  Genetic Position: Chr17, 19.69 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked positive selection cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in the brain at P15 and P30. (J:205651)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf21 Mutation:  45 strains or lines available
References
Original:  J:205651 Mi S, et al., Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination. Nat Med. 2011 Jul;17(7):816-21
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory