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Targeted Allele Detail
Symbol: Rgs16tm1Sia
Name: regulator of G-protein signaling 16; targeted mutation 1, Shinichi Aizawa
MGI ID: MGI:5546629
Gene: Rgs16  Location: Chr1:153616099-153621214 bp, + strand  Genetic Position: Chr1, 65.43 cM
Germline Transmission:  Earliest citation of germline transmission: J:205653
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA lox71 site, lacZ gene, polyadenylation sequence, FRT-flanked neomycin resistance cassette and loxP site replaced the coding sequence from exon 1 through 5. Western blot analysis confirmed the absence of protein expression in the hypothalamic suprachiasmatic nucleus. (J:205653)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs16 Mutation:  4 strains or lines available
Original:  J:205653 Doi M, et al., Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus. Nat Commun. 2011;2:327
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory