Sox9tm2.1Haak
Targeted Allele Detail
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Symbol: |
Sox9tm2.1Haak |
Name: |
SRY (sex determining region Y)-box 9; targeted mutation 2.1, Haruhiko Akiyama |
MGI ID: |
MGI:5546592 |
Synonyms: |
Sox9-EGFP |
Gene: |
Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
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Alliance: |
Sox9tm2.1Haak page
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Germline Transmission: |
Earliest citation of germline transmission:
J:205660
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Parent Cell Line: |
AB1 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1+
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
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Mutation details: An IRES-EGFP-polyadenylation sequence and floxed neomycin resistance cassette were inserted into the first exon. Cre-mediated recombination removed the neomycin resistance cassette. RT-PCR confirmed the absence of transcript expression in EGFP+ cells.
(J:205660)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sox9 Mutation: |
32 strains or lines available
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Original: |
J:205660 Nakamura Y, et al., Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun. 2011;2:251 |
All: |
5 reference(s) |
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