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Targeted Allele Detail
Symbol: Sox9tm2.1Haak
Name: SRY (sex determining region Y)-box 9; targeted mutation 2.1, Haruhiko Akiyama
MGI ID: MGI:5546592
Synonyms: Sox9-EGFP
Gene: Sox9  Location: Chr11:112782224-112787760 bp, + strand  Genetic Position: Chr11, 77.27 cM
Germline Transmission:  Earliest citation of germline transmission: J:205660
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsAn IRES-EGFP-polyadenylation sequence and floxed neomycin resistance cassette were inserted into the first exon. Cre-mediated recombination removed the neomycin resistance cassette. RT-PCR confirmed the absence of transcript expression in EGFP+ cells. (J:205660)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox9 Mutation:  13 strains or lines available
Original:  J:205660 Nakamura Y, et al., Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun. 2011;2:251
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory