Tie1^tm2Vlcg
Targeted Allele Detail

Summary

• Symbol: Tie1^tm2Vlcg
• Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1; targeted mutation 2, Velocigene
• MGI ID: MGI:5546198
• Synonyms: Tie1^LacZ-neo
• Gene: Tie1 Location: Chr4:118328388-118347046 bp, - strand Genetic Position: Chr4, 54.67 cM
• Alliance: Tie1^tm2Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200671
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ/neomycin resistance cassette replaced a portion of the coding sequence including the methionine start site. (J:200671)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tie1 Mutation: 67 strains or lines available

References

• Original: J:200671 Economides AN, et al., Conditionals by inversion provide a universal method for the generation of conditional alleles. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88
• All: 1 reference(s)