Sox9^Bbfc
Chemically induced Allele Detail

Summary

• Symbol: Sox9^Bbfc
• Name: SRY (sex determining region Y)-box 9; babyface
• MGI ID: MGI:5546026
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^Bbfc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: A C-to-T transition mutation results in a threonine to methionine missense mutation at codon 87 (p.T87M). (J:222308, J:223062)
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 32 strains or lines available

References

• Original: J:223062 Palmer K, et al., Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology. Dev Biol. 2016 Jul 15;415(2):216-27
• All: 2 reference(s)