Tg(CYP2A13,CYP2B6,CYP2F1)349Ding
Transgene Detail

Summary

• Symbol: Tg(CYP2A13,CYP2B6,CYP2F1)349Ding
• Name: transgene insertion 349, Xinxin Ding
• MGI ID: MGI:5545879
• Transgene: Tg(CYP2A13,CYP2B6,CYP2F1)349Ding Location: unknown
• Alliance: Tg(CYP2A13,CYP2B6,CYP2F1)349Ding page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CYP2A13,CYP2B6,CYP2F1)349Ding expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CYP2F1 (1572)

  Cyp2f2

  (MGI:88608)

• Mutation details: Human BAC clone CTD-2535H15 containing CYP2A13, CYP2B6, and CYP2F1 genes was linearized with NotI, and purified before microinjection into pronuclei of fertilized eggs. Transcripts of all three genes were confirmed immunologically. (J:204724)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:204724 Wei Y, et al., Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model. Drug Metab Dispos. 2012 Jun;40(6):1144-50
• All: 4 reference(s)