S1pr5^{tm1e(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: S1pr5^{tm1e(EUCOMM)Hmgu}
• Name: sphingosine-1-phosphate receptor 5; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5544956
• Gene: S1pr5 Location: Chr9:21154213-21159739 bp, - strand Genetic Position: Chr9, 7.75 cM, cytoband A4
• IMPC: S1pr5 gene page

Mutation origin

• Mutant Cell Lines: HEPD0952_1_A01, HEPD0952_1_A03, HEPD0952_1_A04, HEPD0952_1_A05, HEPD0952_1_A06, HEPD0952_1_A07, HEPD0952_1_A08, HEPD0952_1_A09, HEPD0952_1_A10, HEPD0952_1_A11, HEPD0952_1_A12, HEPD0952_1_B01, HEPD0952_1_B02, HEPD0952_1_B06, HEPD0952_1_B07, HEPD0952_1_B08, HEPD0952_1_B09, HEPD0952_1_B10, HEPD0952_1_B11, HEPD0952_1_B12, HEPD0952_1_C01, HEPD0952_1_C02, HEPD0952_1_C03, HEPD0952_1_C04, HEPD0952_1_C05, HEPD0952_1_C06, HEPD0952_1_C08, HEPD0952_1_C10, HEPD0952_1_C11, HEPD0952_1_C12, HEPD0952_1_D01, HEPD0952_1_D02, HEPD0952_1_D06, HEPD0952_1_D07, HEPD0952_1_D09, HEPD0952_1_D10, HEPD0952_1_D11, HEPD0952_1_D12, HEPD0952_1_E01, HEPD0952_1_E02, HEPD0952_1_E03, HEPD0952_1_E04, HEPD0952_1_E05, HEPD0952_1_E06, HEPD0952_1_E07, HEPD0952_1_E08, HEPD0952_1_E09, HEPD0952_1_E10, HEPD0952_1_E11, HEPD0952_1_E12, HEPD0952_1_F02, HEPD0952_1_F03, HEPD0952_1_F04, HEPD0952_1_F05, HEPD0952_1_F06, HEPD0952_1_F07, HEPD0952_1_F08, HEPD0952_1_F10, HEPD0952_1_F11, HEPD0952_1_F12, HEPD0952_1_G01, HEPD0952_1_G03, HEPD0952_1_G04, HEPD0952_1_G05, HEPD0952_1_G06, HEPD0952_1_G07, HEPD0952_1_G08, HEPD0952_1_G09, HEPD0952_1_G10, HEPD0952_1_G11, HEPD0952_1_G12, HEPD0952_1_H01, HEPD0952_1_H03, HEPD0952_1_H04, HEPD0952_1_H05, HEPD0952_1_H06, HEPD0952_1_H07, HEPD0952_1_H09
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 21156945 of Chromosome 9 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S1pr5 Mutation: 19 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)