About   Help   FAQ
Pde6btm1Eye
Targeted Allele Detail
Nomenclature
Symbol: Pde6btm1Eye
Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; targeted mutation 1, Stephen H Tsang
MGI ID: MGI:5544444
Synonyms: Pde6bStop
Gene: Pde6b  Location: Chr5:108388373-108431743 bp, + strand  Genetic Position: Chr5, 53.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:200898
Parent Cell Line:  KV1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    A floxed stop cassette was inserted in intron 1 via homologous recombination. (J:200898)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pde6b Mutation:  118 strains or lines available
References
Original:  J:200898 Davis RJ, et al., Therapeutic Margins in a Novel Preclinical Model of Retinitis Pigmentosa. J Neurosci. 2013 Aug 14;33(33):13475-13483
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory